Project: Investigating Drug Adverse Effect on Diabetes and Breast Cancer

Project: Investigating Drug Adverse Effect on Diabetes and Breast Cancer


Overview

With the efficacy and costs of medications rising rapidly, it is increasingly important to ensure that drugs be prescribed as rationally as possible. Recently, adverse drug effects have received intensive attention for it remains a leading cause of morbidity.

Our project, "Investigating the Adverse Drug Effect on Type-2 Diabetes and Breast Cancer," aims at finding out specific research questions as follows:

  • Specific adverse effect of combination drugs since drugs and adverse effects are lumped together in the database;

  • if adverse effect of drugs is observed in various visits of a patient;

  • if adverse effect of drugs is correlated to dosage.

Our preliminary results demonstrated — see below — adverse effects of drugs are dependent on covariates such as age, gender and weight.

Further study on these covariates using propensity matching scores and other statistical methods are under investigation.

Drug adverse events model

Project Update

2019

DrugAssist

DrugAssist is an intelligent medicine recommender system that recommends drugs for patients who are suffering from various diseases. DrugAssist has been successfully upgraded to recommend drugs for patients who are suffering from either breast cancer or Type II diabetes.

More diseases will be added as the project progresses.

The system is currently in beta.