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Paige Adams

Paige AdamsTeaching Assistant Professor of Veterinary Medicine

Contact Info

apadams@k-state.edu
913-307-7367

 

Paige Adams, Ph.D., D.V.M., is a teaching assistant professor at Kansas State University's Olathe campus, where she has served this campus as a faculty member since August 2013. Prior to this, she was an assistant professor and postdoctoral research fellow in the department of pathology at the University of Texas Medical Branch in Galveston, Texas, for nine years

Adams is experienced as a practicing large animal veterinarian, with a specialty in surgery, as well as a research scientist. Her primary research interests include studies of the immune system's response to viruses called arboviruses that are transmitted by mosquitoes as well as vaccine development for important zoonotic diseases.

At the Olathe campus, Adams actively recruits, teaches and supervises students in various graduate programs that focus on animal and human health. She also is involved in professional development programs at the campus that focuses on the regulations of drugs and vaccines for animals. Overall, her experiences as a large animal veterinarian and research scientist of zoonotic diseases make her an ideal fit for graduate programs that focus on the improvement of animal and human health (One Health).

Education

Ph.D., Immunology, Cornell University, 2004

D.V.M., Veterinary Medicine, Texas A&M University, 1993

B.S., Veterinary Science, Texas A&M University, 1990

Research Interests

• Innate and adaptive immune responses to arboviruses (especially alphaviruses and flaviviruses)

• Immunopathology and infectious disease pathogenesis of alphaviruses

• Development of vaccines and other biologics for biodefense and emerging zoonotic infectious diseases

Teaching Schedule

AAI 840 Regulatory Aspects of Drug and Vaccine Development in the Animal Health Industry

DMP 710 Introduction to One Health

DMP 802/MPH 802 Environmental Health

DMP 870 Pathobiology Seminar

DMP 880/FDSCI 961 Problems: Zoonotic Pathogens in the Food Chain

DMP 895 Topics: Vaccinology

Graduate Faculty Service

As a graduate faculty member, Adams has served in the following graduate programs at Kansas State University:

  • Veterinary Biomedical Science (M.S.)
  • Master of Public Health (M.P.H.)
  • Professional Science Master (P.S.M.) in Applied Science and Technology
  • Biological and Agricultural Engineering (M.S.)

Publications/Scholarly Work

Forrester NL, Auguste AJ, Dugan VG, Wortheim JO, Adams AP, Chen R, Gorchakov R, Leal G, Pandya J, Halpin RA, Stockwell TB, Wentworth DE, Smith M, Kosakovsky SL, Weaver SC.  Evolution and spread of Venezuelan equine encephalitis complex alphaviruses in the Americas.  PLoS Negl Trop Dis 2017. 

Seymour RL*, Adams AP*, Leal G, Alcorn MDH, Weaver SC.  A Rodent Model of Chikungunya Virus Infection in RAG1-/- Mice, with Features of Persistence, for Vaccine Safety Evaluation.  PLoS Negl Trop Dis 2015;9(6):e0003800.

Roy CJ, Adams AP, Wang E, Plante K, Gorchakov R, Seymour RL, Vinet-Oliphant H, Weaver SC.  Chikungunya vaccine candidate is highly attenuated and protects nonhuman primates against Disease following a single dose.  J Infect Dis 2014;209:1891-1899. 

Roy CJ, Adams AP*, Wang E, Leal G, Seymour RL, Sivasubramani S, Mega W, Frolov I, Killeen SZ, Didier PJ, Weaver SC. A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus. Vaccine 2013;31:1464-1470. 

Adams AP, Siirin M, Travassos da Rosa APA, Nunes MR, Xiao S-Y, Tesh RB. Pathogenesis of Modoc virus (FlaviviridaeFlavivirus) in persistently infected hamsters. AJTMH 2013;88:455-460.

Adams AP, Navarro-Lopez R, Ramirez-Aguilar F, Lopez-Gonzalez I, Leal G, Flores-Mayorga JM, Travassos Da Rosa A, Saxton-Shaw KD, Singh AJ, Borland EM, Powers AM, Tesh RB, Weaver SC, Estrada-Franco JG. Venezuelan equine encephalitis virus activity in the Gulf Coast region of Mexico, 2003-2010. PLoS Negl Trop Dis 2012;6:e1875.

Zasloff M, Adams AP, Beckerman B, Campbell A, Han Z, Meza I, Julander J, Mishra A, Qu W, Taylor JM, Weaver SC, Wong, GC. Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential. PNAS 2011;108:15978-15983.

Arrigo NC, Adams AP, Watts DM, Newman PC, Weaver SC. Cotton rats (Sigmodon hispidus) and house sparrows (Passer domesticus) as amplification hosts of North and South American strains of eastern equine encephalitis virus. EID 2010;16:1373-1380.

Atasheva S, Wang E, Adams AP*, Plante KS, Ni S, Taylor K, Miller ME, Frolov I, Weaver SC. Chimeric alphavirus vaccine candidates provide complete protection in mice after intranasal challenge with western equine encephalitis virus. Vaccine 2009;27:4309-4319.

Adams AP, Aronson JF, Tardif SD, Patterson JL, Brasky KM, Geiger R, de la Garza M, Carrion R, Jr., Weaver SC. Common marmosets (Callithrix jacchus) as a nonhuman primate model to assess the virulence of eastern equine encephalitis virus strains. J Virol 2008;82:9035-9042.

Wang E, Volkova E, Adams AP, Forrester N, Xiao S-Y, Frolov I, Weaver SC. Chimeric alphavirus vaccine candidates for chikungunya. Vaccine 2008;26:5030-5039.

Aguilar PV, Adams AP*, Wang E, Carrara A-S, Anishchenko M, Frolov I, Weaver SC. Structural and nonstructural genes of eastern equine encephalitis virus are determinants of interferon sensitivity and mouse neurovirulence. J Virol 2008;82:4920-4930.

Wang E, Petrakova O, Adams AP, Aguilar PV, Kang W, Paessler S, Frolov I, Weaver SC. Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice. Vaccine 2007;25:7573-7581.

*Authors contributed equally to this work.

Book Chapters

Adams AP. Veterinary vaccines: Introduction. In: Barrett AD, Milligan GN, eds. Vaccinology. Oxford: Wiley-Blackwell; 2014.

Adams AP. Veterinary vaccines: Regulations and impact on emerging infectious diseases. In: Barrett AD, Milligan GN, eds. Vaccinology. Oxford: Wiley-Blackwell; 2014.