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K-State Olathe

Paige Adams

Vet Med Asst Prof Paige AdamsDr. Paige Adams comes to Kansas State University Olathe from Texas, where she was an Assistant Professor at the University of Texas Medical Branch (UTMB) in Galveston, Texas. Prior to her appointment as Assistant Professor, she was a postdoctoral fellow and instructor at the same university.

Dr. Adams has experience working as a large animal veterinarian. Her primary research interests include studies of the immunopathogenesis of arboviruses as well as the development of vaccines and therapeutics for pathogenic viruses within the genusAlphavirus. This expertise will serve her well as the Business Development Specialist for the U.S.-China Center for Animal Health. Her teaching experience in both graduate and professional programs also makes her a great fit for the Veterinary Biomedical Sciences program at K-State Olathe.

Education

Ph.D., Immunology, Cornell University, 2004
D.V.M., Veterinary Medicine, Texas A&M University, 1993
B.S., Veterinary Science, Texas A&M University, 1990

Research Interests

  • Discovery and characterization of novel therapeutic agents for human and animal viral pathogens
  • Immunopathology and infectious disease pathogenesis of alphaviruses
  • Innate and adaptive immune responses to arboviruses (including alphaviruses and flaviviruses)
  • Development of vaccines and other biologics for biodefense and emerging infectious diseases (human and animal)
  • Phylogenetics and evolutionary processes of arboviruses as they relate to emergence

Publications/Scholarly Work

Roy CJ, Adams AP, Wang E, Leal G, Seymour RL, Sivasubramani S, Mega W, Frolov I, Killeen SZ, Didier PJ, Weaver SC. A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus. Vaccine 2013;31:1464-1470. 

Adams AP, Siirin M, Travassos da Rosa APA, Nunes MR, Xiao S-Y, Tesh RB. Pathogenesis of Modoc virus (FlaviviridaeFlavivirus) in persistently infected hamsters. AJTMH 2013;88:455-460.

Adams AP, Navarro-Lopez R, Ramirez-Aguilar F, Lopez-Gonzalez I, Leal G, Flores-Mayorga JM, Travassos Da Rosa A, Saxton-Shaw KD, Singh AJ, Borland EM, Powers AM, Tesh RB, Weaver SC, Estrada-Franco JG. Venezuelan equine encephalitis virus activity in the Gulf Coast region of Mexico, 2003-2010. PLoS Negl Trop Dis 2012;6:e1875.

Zasloff M, Adams AP, Beckerman B, Campbell A, Han Z, Meza I, Julander J, Mishra A, Qu W, Taylor JM, Weaver SC, Wong, GC. Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential. PNAS 2011;108:15978-15983.

Arrigo NC, Adams AP, Watts DM, Newman PC, Weaver SC. Cotton rats (Sigmodon hispidus) and house sparrows (Passer domesticus) as amplification hosts of North and South American strains of eastern equine encephalitis virus. EID 2010;16:1373-1380.

Atasheva S, Wang E, Adams AP, Plante KS, Ni S, Taylor K, Miller ME, Frolov I, Weaver SC. Chimeric alphavirus vaccine candidates provide complete protection in mice after intranasal challenge with western equine encephalitis virus. Vaccine 2009;27:4309-4319.

Adams AP, Aronson JF, Tardif SD, Patterson JL, Brasky KM, Geiger R, de la Garza M, Carrion R, Jr., Weaver SC. Common marmosets (Callithrix jacchus) as a nonhuman primate model to assess the virulence of eastern equine encephalitis virus strains. J Virol 2008;82:9035-9042.

Wang E, Volkova E, Adams AP, Forrester N, Xiao S-Y, Frolov I, Weaver SC. Chimeric alphavirus vaccine candidates for chikungunya. Vaccine 2008;26:5030-5039.

Aguilar PV, Adams AP, Wang E, Carrara A-S, Anishchenko M, Frolov I, Weaver SC. Structural and nonstructural genes of eastern equine encephalitis virus are determinants of interferon sensitivity and mouse neurovirulence. J Virol 2008;82:4920-4930.

Wang E, Petrakova O, Adams AP, Aguilar PV, Kang W, Paessler S, Frolov I, Weaver SC. Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice. Vaccine 2007;25:7573-7581.

 

 

Contact

Dr. Adams can be reached at apadams@k-state.edu or
913-307-7367.

View her CV (pdf)